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import wx
class MyFrame(wx.Frame):
    def __init__(self, parent, title):
        wx.Frame.__init__(self, parent, -1, title )
        btn = wx.Button(self, -1, "Hola")
        self.Bind(wx.EVT_BUTTON, self.say_hello, btn)
 
    def say_hello(self,*arg):
        print "hola todo el mundo!"
 
class MyApp(wx.App):
    def OnInit(self):
        frame = MyFrame(None, "Simple wxPython App")
        frame.Show(True)
        return True
MyApp().MainLoop()